Fertility News
Fertility News
Global fertility updates, research signals, policy shifts, and clinic-facing news collected in one place.
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Only One Fertilized Egg: Is Day 5 Always the Better IVF Strategy?
With only one fertilized egg, should IVF patients wait for a Day 5 blastocyst or consider an earlier transfer? Research comparing transfer strategies highlights a hidden trade-off: stronger results per transfer can coexist with fewer patients reaching transfer at all. The choice depends on more than embryo stage.
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NMN for Egg Quality: Rejuvenation Breakthrough or Evidence Still Waiting?
Can NMN improve egg quality or reverse ovarian aging? Early human research and registered IVF trials are bringing this NAD+ precursor into fertility discussions. But laboratory findings, egg maturation and live birth are different endpoints—and an egg rejuvenation claim remains ahead of the evidence.
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Embryo Transfer Technique: Does the Doctor’s Touch Matter?
Embryo transfer takes only minutes, but could the doctor performing it influence IVF outcomes? Studies of learning curves and differences between operators suggest that technique deserves attention alongside embryo quality. Procedure volume, difficult transfers and the limits of observational comparisons complicate the picture.
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Miscarriage After a Euploid Embryo Transfer: How Can “Normal” Still Go Wrong?
Why can miscarriage happen after a PGT-A euploid embryo transfer? Chromosome screening samples a small group of cells rather than certifying every part of an embryo. Mosaicism, genetic changes outside the test’s scope and maternal factors help explain why a normal result cannot guarantee live birth.
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Non-Invasive Embryo Testing: Can a Drop of Culture Medium Reveal Chromosomes?
Could spent embryo culture medium reveal chromosomal status without a biopsy? A small pilot study explored metabolic differences between euploid and aneuploid embryos. The reported predictive accuracy is intriguing, but this early research does not establish a replacement for PGT-A.
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IVF Culture Medium and Live Birth: Can a Few Drops Make a Difference?
Does the choice of IVF culture medium affect cumulative live birth? A Dutch randomized trial compared two commercial media and found different rates, alongside differences in laboratory outcomes. The primary adjusted comparison did not reach conventional statistical significance, leaving an important question open.
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Rescue IVM: Can Immature Eggs Mature After Retrieval?
In a selected group of 47 women younger than 39, rescue culture matured 127 of 266 GV oocytes and produced additional euploid embryos and live births. Lower blastocyst development, small sample size and inconsistent reporting limit interpretation.
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Missed the LH Surge Before FET? Progesterone May Offer Another Timing Clue
Does missing the LH surge mean a natural-cycle frozen embryo transfer must be abandoned? A prospective study compared transfer timing based on progesterone rise with timing based on LH. Similar observed live birth outcomes raise a practical monitoring question, without establishing a rule for every clinic or cycle.
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Day 7 Blastocysts: Late to Develop, but Too Soon to Give Up?
Can Day 7 blastocysts lead to live birth? A review of retrospective IVF studies found lower average success than with Day 5 or Day 6 embryos, including in euploid comparisons. Lower odds, however, do not make the chance zero—especially when few embryos are available.
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Mounjaro Babies: A Fertility Boost—or a Contraception Gap?
Why are unexpected pregnancies being called “Mounjaro babies”? Weight loss, changing ovulation patterns and tirzepatide’s interaction with oral contraception offer different pieces of the story. These medicines are not established fertility treatments, and pregnancy planning requires attention to product-specific safety guidance.
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Adenomyosis, Endometriosis and IVF Pregnancy: Why Two Lines Are Not the Finish
After IVF success, how do adenomyosis and endometriosis relate to pregnancy risks? A study of women who gave birth following IVF or ICSI examined preterm delivery, placental complications and hypertension. The findings shift attention from implantation to prenatal care, without predicting an individual pregnancy’s outcome.
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Heat and IVF Egg Retrieval: Can Summer Temperatures Leave a Small Trace?
Could hotter weather before IVF egg retrieval be linked with fewer eggs? A large observational study found small associations between apparent temperature and oocyte yield. The findings invite investigation of environmental exposures; they do not mean a heat wave destroys eggs or determines a patient’s result.